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Blog Post, Case Study, Drug Discovery

De-noising CMap L1000 Data

The Connectivity Map (CMap) is a conceptual, comprehensive linking of cellular signatures to genomic (i.e. mutation) and pharmacological (i.e. drug-mediated) effects. The CMap dataset is based on the L1000 assay (developed by the Broad Institute), which measures the mRNA abundance of 978 landmark genes plus 80 control genes from human

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